This individual will perform microbial fermentations to produce recombinant proteins using soluble and insoluble expression systems.
These efforts will be towards scale down characterization studies to support Validation efforts and Manufacturing process.
The client is seeking a highly motivated individual with proven abilities who will be involved in the execution and analysis of upstream fermentation experiments.
We expect the successful candidate to contribute to the group by collaborating ...
My name is Domenic and I represent The Fountain Group. We are a national staffing firm and are currently seeking an Associate Research Scientist I for a prominent client of ours. This position is located in Emeryville, CA. Details for the positions are as follows:
§ Experience operating microbial fermentors and using fermentation software packages
§ Ability to plan and execute basic protocols such as flask experiments Mechanical Aptitude and ability to trouble ...
Major developer of novel renal therapeutics seeks Phd with thorough understanding of renal disease pathophysiology and detailed experience performing small animal handling and surgery to provide hands-on leadership in the design and execution of pharmacology experiments and in vivo studies to evaluate new renal therapeutic drug candidates.
This includes, but is not limited to: developing and characterizing mouse models of kidney disease, running in vivo screening cascades to support lead ...
Seeking PhD, ability to design and conduct in vitro cell based assays, stem cell differentiation, and biochemical assays, and a history conducting muscle and biological fluid histological analysis to lead a team of scientific professionals performing:
*** Development and execution of cell based assays to support mechanism of action and target validation studies.
*** Biomarker discovery and translational studies to refine mechanistic understanding of molecular targets in chronic kidney disease.
Seeking PhD and 2+ years experience in formulating delivery methods such as metered dose inhalers, dry powder inhalers, nasal sprays, and nebulizers.
Must be familiar with:
*** Quality by Design and Design of Experiments protocols.
*** Formulation and analytical expertise with particle sizing, blending, in vitro permeation testing, and rheometry.
*** Aerosol and powder characterization: cascade impaction, moisture sorption isotherm, bulk density, surface area.
*** Scale-up, tech transfer, ...
Seeking leader with 10+ years in pre-clinical drug discovery and Ph.D. in cellular or molecular immunology or MD with training in respiratory, inflammation or autoimmune disorders and a track record of successfully moving drug leads through discovery process to clinical phase.
*** Track record managing operational budgets.
*** Ability to recruit, lead and develop top rated scientists in a multi-task extremely fast-paced environment and constantly changing priorities.
Seeking a proven leader with experience leading preclinical research of novel protein therapeutics for autoimmune diseases.
Shall manage the following activities:
*** Target discovery, translational research, biomarker assay development, mechanism-of-action studies, In Vitro and In Vivo models
*** Establishing and managing strategic collaborations with pharmaceutical and academic organizations
*** Supervising up to 10 scientists
Candidate must possess 10+ years of experience and PhD in ...
To develop and improve analytical testing methods for microbially produced diagnostic antigen products and to assist in method transfers to QC.
Assist in development of state of the art analytical methods for testing of protein antigen products that reliably and reproducibly meet Novartis Diagnostics business requirements Assist in the implementation of new analytical technologies and improvement of existing technologies in the group Prepare and review scientific experiment protocols and reports ...
• Develop and improve analytical testing methods for microbially produced diagnostic antigen products and to assist in method transfers to QC.
• Assist in development of state of the art analytical methods for testing of protein antigen products that reliably and reproducibly meet client’s business requirements
• Assist in the implementation of new analytical technologies and improvement of existing technologies in the group
• Prepare and review scientific experiment protocols ...
• Design and execute purification process validation studies for yeast and E. coli antigens, including drafting of protocols, technical reports and supporting documents.
• Support manufacturing data review, investigation efforts
• Subject matter expert on cross-functional teams for validation, manufacturing efforts
• On an as needed basis, provide technical guidance to research associates in group
8-10 years experience in purification process ...
We are looking for a highly motivated individual to join our Small Molecule Open Access and Expert Purification team (part of the Analytical Group) that supports Medicinal Chemistry.
The successful candidate will demonstrate a high level of creativity and independence in designing new high throughput small molecule purification and analytical functions
• Demonstrates highly productivity in high throughput purification and is able to lead the purification ...
Cutting edge opportunity in research and development involving lead drug candidates to: resolve analytical challenges; propose, test, and develop alternate analytical methods; collaborate closely with the manufacturing controls and R&D scientists involved in discovery of new drug product candidates; independently manage projects; organize and summarize analytical data, review against product specifications, chart trends, and keep team informed; and coordinate maintenance of laboratory equipment, ...
Seeking 5+ years’ experience analyzing pharmaceutical products using:
*** High Performance Liquid Chromatography
*** Diode Array Detection HPLC
*** Thin Layer Chromatography
*** Ion Chromatography
*** Gas Chromatography – Mass Spectrometry
*** Liquid Chromatography – Mass Spectrometry
*** Nuclear Magnetic Resonance
*** Fourier Transform Infrared Spectroscopy
*** Inductively Coupled Plasma Mass Spectrometry
Cutting edge opportunity in research and development involving lead drug ...
Apr 2 -
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